Xenobiotic Laboratories (XBL), a subsidiary of the Lab Testing Division of WuXi AppTec, Inc., is a leading contract research laboratory specializing in small molecule Bioanalytical, drug metabolism, and pharmacokinetic services to the pharmaceutical, animal health and agrochemical industries. XBL is seeking a Research Scientist to join our Bioanalytical Department.
Develop and validate animal health bioanalytical assays using LC-MS/MS.
Perform bioanalytical sample testing for PK/TK studies.
Perform extraction of plasma, tissue samples, LC-MS/MS instrument operation, maintenance and troubleshooting.
Trained in SOPs.
Write method development and bioanalytical report.
Present experimental results. Working with other scientists in studies.
Solid understanding in analytical chemistry.
Expert in chromatography , solvent, buffer, and reagent preparations and applications.
Must possess li Analytical Chemistry skills; LC-MS (API4000 or 5000 preferred), Shimadzu HPLC systems, and troubleshooting.
Experience in LC-MS/MS, bioanalytical assay development, validation, and sample testing.
Experience in dose formulation assay development, validation, and sample assay by LC/MS and LC/UV.
Experience with radioisotope handling (e.g., 3H, 14C) biochemical techniques is a plus.
Must possess experience in Good Laboratory Practice (GLP) and have a thorough understanding of any industry, FDA, or other applicable regulatory guidance pertaining to the conduct of bioanalytical activities.
M.S. degree in chemistry, biology, or a related discipline, or equivalent with at least 5 years of relevant laboratory experience in LC-MS/MS bioanalysis
Any similar combination of education and experience
Knowledge of commonly used scientific concepts, practices, and procedures within pharmacology or animal science field
Well organized, detail oriented, and adaptable to changes
Effective oral and written communication skills
Effective interpersonal skills
Computer skills: knowledge of internet research, MS Word, Excel, Outlook, and PowerPoint
Knowledge of Laboratory Information Management System (LIMS)
Knowledge of Data Acquisitions and Operating Software as Analyst, MassLynx….
Up-to-date knowledge of Bioanalytical techniques in method development and sample analysis of analyte and its metabolites in biological matrices.
Ability to work under pressure of multiple projects and deadlines
Ability to effectively prioritize workload and manage changes in direction
Ability to work in a team environment
Familiarity with and adherence to regulatory guidelines consistent with XBL requirements