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Research Scientist- PI Chemist (US-NJ-Plainsboro)

Overview:

  • Xenobiotic Laboratories (XBL), a subsidiary of the Lab Testing Division of WuXi AppTec, Inc., is a leading contract research laboratory specializing in small molecule Bioanalytical, drug metabolism, and pharmacokinetic services to the pharmaceutical, animal health and agrochemical industries. XBL is seeking a Research Scientist to join our Bioanalytical Department.
  • Key Accountibilities:

  • Develop and validate animal health bioanalytical assays using LC-MS/MS.
  • Perform bioanalytical sample testing for PK/TK studies.
  • Perform extraction of plasma, tissue samples, LC-MS/MS instrument operation, maintenance and troubleshooting.
  • Trained in SOPs.
  • Write method development and bioanalytical report.
  • Present experimental results. Working with other scientists in studies.
  • Solid understanding in analytical chemistry.
  • Expert in chromatography , solvent, buffer, and reagent preparations and applications.
  • Must possess li Analytical Chemistry skills; LC-MS (API4000 or 5000 preferred), Shimadzu HPLC systems, and troubleshooting.
  • Experience in LC-MS/MS, bioanalytical assay development, validation, and sample testing.
  • Experience in dose formulation assay development, validation, and sample assay by LC/MS and LC/UV.
  • Experience with radioisotope handling (e.g., 3H, 14C) biochemical techniques is a plus.
  • Must possess experience in Good Laboratory Practice (GLP) and have a thorough understanding of any industry, FDA, or other applicable regulatory guidance pertaining to the conduct of bioanalytical activities.
  •  Requirements:

  •  Ph.D. degree in chemistry, biology, or a related discipline, or equivalent
  • 1-2 years of relevant laboratory experience in LC-MS/MS bioanalysis
  • Any similar combination of education and experience
  •  Knowledge of commonly used scientific concepts, practices, and procedures within pharmacology or animal science field
  • Well organized, detail oriented, and adaptable to changes
  • Effective oral and written communication skills
  • Effective interpersonal skills
  • Computer skills: knowledge of internet research, MS Word, Excel, Outlook, and PowerPoint
  • Knowledge of Laboratory Information Management System (LIMS)
  • Knowledge of Data Acquisitions and Operating Software as Analyst, MassLynx….
  • Up-to-date knowledge of Bioanalytical techniques in method development and sample analysis of analyte and its metabolites in biological matrices.
  • Ability to work under pressure of multiple projects and deadlines
  • Ability to effectively prioritize workload and manage changes in direction
  • Ability to work in a team environment
  • Familiarity with and adherence to regulatory guidelines consistent with XBL requirements